WNT Signaling and Implications for Dental Regenerative Medicine

نویسندگان

  • Rozaliya Tsikandelova
  • Antonia Isaeva
  • Nikolay Ishkitiev
چکیده

WNT signaling pathway functions throughout the lifetime of the organism by ensuring the normal patterning of tissues during development and by regulating selfrenewal and cell fate commitment in multiple adult stem cell types. Currently, not enough is known about the role of WNT signaling in the maintenance of adult dental tissues. In this review we briefly outline current developments in the field of WNT signaling with regard to the regulation of mesenchymal dental pulp cells and pose outstanding questions to be addressed in the future.

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تاریخ انتشار 2015